Breaking News:

PPD’s Accelerated Enrollment Solutions Acquires Global Site Business from Bioclinica Addition of clinical research sites advances the AES strategy to become the world’s largest patient access and site conduct organization

The new standard in clinical trial productivity.

More patients from fewer sites in less time.

AES owns the most fully identified patient data. And we own the world’s largest network of clinical research sites. Put them together and you get the only solutions for global patient delivery that offer total certainty of budget, time, speed, and quality.

Synexus, Acurian, and Optimal are now AES.

Synexus now represents our site network capabilities, the largest in the world and growing. It’s the same great sites, now part of AES solutions.

Acurian now represents our core patient enrollment services, available globally. These services are underscored by the most fully identified patient data available for trials.

Optimal now represents the services we offer in both vaccines and oncology, using the same great sites but enhanced and extended with AES firepower.

The strong legacy of these companies is now reflected in our full suite of AES services. Combined, these services address site selection and patient enrollment in ways that no other company can – resulting in the new standard of clinical trial productivity.

Global Site and Enrollment Services


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Combined site network and patient enrollment services

SynexusPlus combines AES’s global site network services with supercharged patient recruitment capabilities to provide a competitive strategy for trial enrollment. Through proprietary feasibility and high enrolling global sites, SynexusPlus delivers up to 80% of the patients you need, in less time and from a more efficient site footprint. This combined solution is best suited for clinical trial sponsors or CROs who are in the trial planning phase and have not yet determined their strategy for sites and countries.

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Optimal Vaccine Centers of Excellence

Site network and enrollment services for vaccines

Optimal Vaccine Centers of Excellence (OVCoE) supercharges the world’s largest vaccine site network with accelerated patient enrollment, advanced lab capabilities, and specialized vaccine services – all delivered under a results-based contracting model for total budget certainty. With OVCoE, the leading global site network (Synexus) and leading vaccine specialists (Optimal) combine to optimize productivity and efficiency for vaccine clinical trials.

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Combined CRO, site network, and patient enrollment services

PatientAdvantage is a comprehensive, accelerated clinical trial strategy, based on a patients-first approach. This combined solution includes patient enrollment, global sites, and core CRO services, and delivers up to 100% of the patients needed. The results are unparalleled speed and budget certainty, including fixed price contracts that cover both direct and indirect fees at a price per patient. PatientAdvantage, for sponsors who fully outsource, should be engaged in the trial planning phase to maximize the benefits of this combined solution.


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Synexus Site Network

Site network services

Synexus is the world’s leading site network for clinical trials, offering unmatched capabilities to help biopharmaceutical and CRO customers find the right patient for the right trial at the right time. The Synexus global site network includes nearly 200 clinical research facilities, providing data-driven site selection and activation expertise across the U.S., Europe, Africa, and India.

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Acurian Patient Engagement

Patient enrollment, concierge, and retention services

Acurian is the leading full-service patient enrollment and retention solution, offering a patient-centric approach to increase the enrollment performance of trial sites. Site enrollment rates increase by an average of 50% using this approach that rapidly sources, pre-screens, and delivers high-quality patients who live near – but are unknown to – clinical research sites. Fully identified data is at the heart of the solution and includes more than 100 million households with one or more opted-in patients, and more than 20 million patients who have already pre-screened across thousands of previous clinical trials.

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Optimal Just-in-Time Enrollment

Enrollment augmentation for oncology trials

Optimal Just-in-Time (JIT) jumpstarts oncology trial enrollment and delivers the first patient faster, then continues to find patients to accelerate overall timelines. The Optimal JIT solution includes a community of 300 oncology research sites, all pre-contracted, pre-qualified, and ready for rapid activation into a trial. This solution methodology means no site is initiated or paid until it has pre-identified an eligible patient and is approved by the sponsor. On approval, it takes only two weeks to activate the site and offer the study to the patient. The result is cancer patients get the treatment they need, in the community where they live, from the physicians they trust, surrounded by the people they love.